When Radiesse is injected, it is very common for the physician to gently mold it into the desired position and to smooth out small bumps under the surface. It can be inadvertently moved out of its ideal position for a while afterward. How long until it is well "set"? No one can say with certainty, but I always instruct my patients to be careful for at least three weeks after Radiesse. This includes avoiding facials, Clarisonic cleanser, and even dental work for 3-4 weeks after I've injected them. It is an investment worth protecting!
As for your doctor applying "lots of pressure" when injecting Botox, I feel there is no need to do this routinely, and worth your questioning him about it. Certainly remind him if you've recently had Radiesse; if it was more than a month ago, then no worries.