How Do Stem Cell Under Eyes Help the Darkness?

Many plastic surgeons who perform structural fat grafting report that patients often describe a variety of improvements in their facial skin following fat grafting surgery. This observation has led to the use of fat grafting in reconstructive surgery, for instance in the management of chronic wounds such as those seen in some patients following radiation treatment for cancer. Fat grafting into the tissues below a chronic, non-healing wound has been shown to stimulate successful wound healing in a number of studies.

So what is responsible for this effect? Many of us suspect that it is produced by 'stem cells' which are known to be present in abundance in human adipose (fatty) tissue. Stem cells are very dynamic human cells which have the capacity to be transformed into any number of cell types (fat, muscle, skin, fascia, etc), and which are capable of producing a variety of proteins which promote the repair of damaged cells and tissues.

Much of the evidence has been anecdotal, i.e. the personal observations of physicians made while treating patients in their usual clinical practice, outside the setting of a specific scientific study. A great deal of basic science research is now being done to specifically determine cause and effect, and it is certain that over the next few years we will gain a much clearer understanding of the healing properties of fatty tissue and stem cells.

Be aware that the term 'stem cell' is increasingly being used in what I feel may be an irresponsible manner - as a marketing gimmick to attract patients to a particular practice or surgeon. Nobody has an exclusive claim or right to the use of stem cells, and as yet no one has demonstrated an objective, quantitative method for measuring any 'stem cell effect' in facial rejuvenation surgery, if it is truly present. I believe that this effect exists, but it currently is not objectively and reproducibly measurable and therefore should not be used to 'sell' surgery.

There been a great push to use stem cells for Facelift,eye lift and every thing else. There is no scientific data to support it. Using fat grafting(that has stem cells in it )is effective and much cheaper.

The question of how stem cells improve the areas under the eyes (darkness and depressions) is really an open question. The data from clinical trials is mixed and some physicians and patients swear by stem cells while others do not see a difference.

The potential for stem cell is probably huge. Stem cells harvested from fat or from skin retain the ability to make all types of cells and many different growth molecules. The methods for stimulating them to do this are being worked out.

My impression is that stem cells may not be the answer for dark circules under the eyes yet.