Wrinkles around the mouth following lip dissolving and weight loss - how can I fix this? (Photos)

Hi there! I’m Lauren, the aesthetic provider here at Colorado Plastic Surgery Center. When filler is dissolved and facial volume drops at the same time, it’s very common for natural expression lines to feel more noticeable. At 25, this is less about aging and more about structure and movement.
A light approach usually works best. Small amounts of filler around the mouth can soften the lines without recreating that “overfilled” look. Skinvive is another great option to improve hydration and smoothness from within. If we want something more long-term, Sculptra can help stimulate your own collagen in the area.
Often, it’s just about restoring a little support so you feel confident smiling again, not changing your features. A quick evaluation in person with your injector will help determine the most natural route for you.

Subtle midface filler (cheeks): Re-supports the area above the mouth so folds don’t deepen when you smile.

Tiny amount of filler in the nasolabial area or oral commissures: Softens lines without recreating an “overfilled” lip look.

Skin boosters or injectable hydrators (e.g., Profhilo, Skinvive, Volite): Improve elasticity and fine lines by hydrating from within, not changing shape.

Botox “lip flip” or micro-dosing around the mouth can gently relax overactive muscles that crease the skin, if movement is the main cause.

It’s completely understandable to feel self-conscious after noticing new lines—especially following such positive changes like weight loss and returning your lips to a more natural shape. What you’re experiencing is very common and often a mix of volume loss and skin elasticity changes that become more visible once filler is dissolved or facial fat decreases with weight reduction.

When filler is removed and subcutaneous fat diminishes, the skin that was once slightly stretched can appear looser, revealing lines that weren’t as noticeable before. These aren’t true “wrinkles” from aging, but rather a result of the skin adjusting to less internal support.

Here are a few approaches that can help improve this:

Subtle, strategic filler placement: A very conservative reintroduction of filler—focused around the perioral area (not just the lips)—can restore smoothness and structure without overfilling.

Skin boosters or biostimulators: Treatments such as hyaluronic acid skin boosters (like Profhilo or Volite) or collagen stimulators (like Sculptra or Radiesse) can improve elasticity and hydration, leading to a firmer appearance over time.

Microneedling or radiofrequency (RF) treatments: These can tighten the skin and improve texture naturally by stimulating collagen production.

Topical retinoids or peptides: Continue with good skincare but consider adding gentle retinol or peptide-based products that promote collagen remodeling.

At 25, your skin has great regenerative potential, and these fine lines are very likely to respond beautifully to conservative, targeted treatments. It’s often about restoring a little balance—rather than adding bulk—and helping your skin regain firmness and smoothness as it adjusts.

For the lines around the lips you can consider some filler. Other options to keep skin looking healthy include Morpheus8 treatments and medical grade skin care. Morpheus8 combines RF technology with microneedling to improve overall skin tone and texture. We recommend medical grade skin care products like Transform MD and wearing sunscreen every day.