Sculptra granuloma risk? Are some people more prone to developing granulomas from fillers?

May 25, 2025
Asked By:Luminous2773 in Scotland, United Kingdom

While I was visiting the UK (I live in the US), I had Hyacorp MLF 1 filler injected into the indentations on my inner thighs. These indents were caused by receiving too many radiofrequency (RF) treatments. Unfortunately, the Hyacorp filler led to the formation of granulomas—red, inflamed bumps that flare up intermittently. I’ve been using Triamcinolone cream, which helps calm the inflammation when it flares, but the indents themselves haven’t improved. I’m now considering Sculptra as an alternative, but I’m worried it could also cause granulomas. I understand Hyacorp is hyaluronic acid-based and can be dissolved, but Sculptra cannot. That makes me hesitant. My questions are: Are some people more prone to developing granulomas from fillers? Given my reaction to Hyacorp, should I avoid Sculptra? If so, is there another injectable you would recommend that is both effective for volume loss and has a lower risk of granuloma formation?

1 photo

Answers (1)

From board-certified doctors and trusted medical professionals
MOST RECENT
May 30, 2025

Answer: Granuloma Risk with Injectable Fillers: Considerations for Sculptra and Alternatives

Anna Chacon, MD, FAADBoard Certified Dermatologist
MOST RECENT
May 30, 2025

Answer: Granuloma Risk with Injectable Fillers: Considerations for Sculptra and Alternatives

Anna Chacon, MD, FAADBoard Certified Dermatologist

Recommended reading

Sculptra

Everything you need to know about Sculptra

  • 81% worth it
  • 696.0k reviews
  • Avg cost: $2,053
Learn More
ADVERTISEMENT
ADVERTISEMENT

Recommended reading

Sculptra

Everything you need to know about Sculptra

  • 81% worth it
  • 696.0k reviews
  • Avg cost: $2,053
Learn More
ADVERTISEMENT