Can one get Botox to soften an overactive muscle in the cheek?

If you have an overactive muscle a small amount of Botox may improve your concerns, however it could also lead to an asymmetric smile.  I encourage you to begin by visiting with a board certified plastic surgeon near you.  After an examination and discussion of your concerns the appropriate treatment can be recommended.

As a neuromodulator, Botox is designed to work on overactive muscles. However, use of the product in this area would be off-label. Another option might be well-placed dermal fillers on the side of the face that requires correction. No matter what treatment you choose, make sure you work with a board-certified dermatologist with expertise in injectable fillers to ensure an optimal outcome from your procedure. 

Thank you for your question! Even though, Botox in this area would be considered off label, it could be used depending on what specific muscle is contributing to the asymmetry. You would want to be assessed by an experienced injector. Best of luck to you!

This would be considered an off label use of botox and I'd suggest being cautions.  Incorrect placement of botox in this area could result if a crooked smile.

Good question. This would be an off label use of the product, but it is possible to use the neurotoxin on a specific cheek muscle to help with your smile related issues. If you go to a non surgeon injector, you will get the simple answer of no its not possible. Anywhere from 4-8 units should do it.