Can PRP be performed under local anesthetic?

Hello,
Prp treatment can be done with or without local anesthesia, I dont think it is necessay, however it is possible

Concentrated PRP is very acidic in nature and has a warm, 'stinging' feeling for about 5-10 minutes post-injection. This can be cooled down with ice. Injections in the scalp overall are not favorable, so applying a local anesthetic is recommended. I personally like to apply lidocaine 2% to the scalp with a dental syringe, which isn't too harsh for an injection needle. Some of my patients have done PRP without local numbing and they actually do fine. Our office also offers nitrous gas for relaxation and numbing as well. 
Best, 
Dr. Anil Shah

Most of not all PRP treatments for cosmetic reasons are done under local anesthesia. Lidocaine 1 to 2 percent is what is usually used if injected or in cream form , a lot of Dr’s use BLT cream Benzocaine, Lidocaine , Tetracaine.

 PRP can be done under local anesthesia however, it is not the preferred method as there can be untoward side effects. If PRP is performed using the subdermal depo injection technique and a 30 gauge needle the pain level is less than 2 out of 10. Finally, a new device called Pronox which is 50% nitrous oxide / 50% oxygen can be utilized with the subdermal depo injection technique for a virtually pain-free injection process. Find a PRP expert. Ask to see photos.Jeff Rapaport MDCore Aesthetic Realself

Local anesthesia is the preferred method. Typically I'm able to get by with a specially compounded anesthetic cream I have made for me that on occasion I may augment with an anesthetic known not to damage cells. 
The PRP injection target is not intramuscular. The target is where the hair follicles are.
Hope I have helped.  
Warmly,
Arbella Sarkis, MD

PRP can be done under local anesthesia.  It usually is done after a topical anesthesia has been placed on the treated area.  There is no discomfort with the topical anesthesia cream.  Whereas local injected lidocaine is usually not needed.  

Yes, PrP can be done with local anesthesia. 0.5% to 1% lidocaine with epinephrine (1:100,00 a 1:200,000) is the preferred anesthetic.