Can Hyaluronidase remove Aquamid filler done on cheeks?

Longterm filler problems include migration, edema, and nodularity. Filler migration and permanence is a very common problem because there are many different types of HA fillers on the market and each is specified for a specific part of the face. Use of highly cohesive fillers on thin skin may cause swelling and nodularity. If patients have filler migration or nodules, we recommend a combination approach of filler reversal with enzymes Hylenex and Hyaluronidase in different strengths to dissolve the filler. We may also need to add Kenalog to the mix in order to reduce fibrous tissue. If the filler does not dissolve, it either means the filler is not HA material or we need more enzyme. The HA reversal can be combined with other lasers and skin treatments at the same time, and it usually (usually) does not affect adjacent tissue.

Best,
Dr. Karamanoukian
Realself100 Surgeon

Hyaluronidase does not remove Aquamid, which is a permanent filler made of polyacrylamide spheres.  In the past I've removed Aquamid with surgery when it caused a serious contour abnormality. 

Hello, thank you for your question. The answer is no, hyaluronidase cannot remove Aquamid filler, which is a permanent filler. Hyaluronidase only works to remove hyaluronic acid fillers. In order to remove Aquamid, you will have to undergo a surgical procedure.