I have developed a resistance to Botox, Dysport and Xeomin. Are there any other options or suggestions?

ThermiRase uses injectable radiofrequency to direclty affect the nerves that allow the muscles of the mid lower forehead between the eyebrows to contract.  ThermiRase is not used for crows feet or other facial areas.There is significant swelling and possible bruising with ThermiRase so unlike Botox it is not a "no downtime" procedure. The swelling will last more than a week for most people. Local anesthetic has to be used during the procedure and I often provide other medication to make our patients comfortable so they arrange to have someone bring them home. A thorough consultation is needed to see if someone is a candidate during which I examine the anatomy and actually stimulate the nerves to see if we can use ThermiRase on them. Blood thinners are stopped before the procedure. The results can be more than two years.The information provided in Dr. Shelton's answer is for educational purposes only and is not intended to constitute medical advice.  The information provided should not be relied upon as a substitute for consultations with a qualified health professional who may be familiar with your individual medical needs

Alternatives to Botox/Xeomin/Dysport would be a combination approach with fillers, lasers and microneedling/prp. I recommend getting a formal evaluation with a cosmetic dermatologist. Best, Dr. Emer

It is very rare to develop a resistance to Botox, but it is possible.  In my experience, if someone has truly developed a resistance, it is a resistance to all brands of neurotoxins. I have not found anyone who was resistant to one that was not resistant to all of them.  There may be some surgical or invasive procedure options for you, but no non-surgical ones of which I'm aware.