Is ok to mix Radiesse with Restylane in the cheek area?

Question

Its my first time getting fillers in the cheeks, and this is a ''new technique'' that My injector is recommending, only 1 syringe with cannula for both cheeks. I always read that Radiesse doesn't have an ''antidote'', and that makes me nervous, even though my injector is highly experienced. Most of the people use Voluma in that area, that's why I'm wondering if any of you are familiar with the Radiesse/Restylane mix and if the results are better than with a hyaluronic acid filler? Thank you!

Jason Emer, MD · Answer

I often frequently injecting multiple filler types in the same session to contour and shape the face and other parts of the body.  What matters most is who is doing the injecting.  It is important to find someone with experience in all the filler types and who uses a cannula for injection of larger areas as it limits complications and can improve contouring.  Best, Dr. Emer.

Francis Johns, MD · Answer

Thank you for your question.I think the type of filler used, it based on the injector. Everyone has their preference on what they like to use in different areas. And there is more than one product that can be injected in these areas. It is fine to mix products, there is nothing that says you cannot do this.

Michael I. Echavez, MD · Answer

While it would be okay to use Radiesse and Restylane together in the cheek area, I normally would just use one or the other.  I don't like to mix different fillers at the same time to the same area.  If you had had Restylane in the past and then wanted to change to Radiesse, that would be fine.  Voluma or Restylane or Radiesse could all be used in the cheek area.  I think that Voluma would be the longest lasting, then Radiesse and then Restylane.

Toby Mayer, MD · Answer

I don’t know why you would need those two particular cheeks fillers. I always use Voluma for this purpose if it is placed for overall cheek volume loss. The Voluma is placed at the bone and not in the skin. It is totally reversible and lasts two years.

Robin A. Sykes, MD · Answer

The two products can be layered or used together safely.  Personally I usually use Radiesse alone in the cheeks, finding the Voluma not robust enough to produce the effect that I am looking for without using a lot more product.  I will use it if the person has thin skin and I want a softer effect.  A cannula in the hands of an experienced injector should produce a good result.  Cannulas are nice to use, because they can minimize pain, bruising, and the number of "holes" in the skin. I use them a lot in my practice.

Amy Y. Paul, DO, FAAD · Answer

Thanks for your question.  I am having a little hard time understanding what your injector plans on doing exactly.  Do you mean they are going to inject one syringe of Radiesse, split between the two cheeks, as a volume enhancer?  That would be a perfectly ok option and Radiesse, while not a hyaluronic acid filler, does eventually dissolve completely and is not permanent or semi-permanent.  The upper cheeks are fairly forgiving and you most likely will not have any problems with Radiesse in that area.   Or is your injector proposing that she or he mix some Restylane with the Radiesse?  That would be a very unusual approach as the products are different and have different properties and uses.  Restylane is a hyaluronic acid filler, and is dissolvable with hyaluronidase, but is not the best filler for placing deep in the cheeks for volume replacement.  I would definitely have a discussion with your injector and make sure he or she is very experienced with any unorthodox techniques or product combinations before agreeing to be a test subject.  See an expert, and best of luck!

Charles Cheng, MD · Answer

In general, it is best not to mix two different products in vitro prior to injection.  Typically there is not enough scientific studies on the effect of mixing two products on the interaction of the ingredients, longevity, results and most importantly safety.
Radiesse if used properly as a collagen production stimulant has excellent results in the cheeks area.  In experienced hands, you shouldn't have any issues.  You can also ask your provider about adding Ultherapy or other energy devices to further stimulate collagen production either pre or post Radiesse injection.
HA fillers such as Restylane, Juvederm....etc. can also offer excellent results.
Mixing Radiesse and HA filler has its challenges and probably best avoided until a protocol has been studied well and proven additional benefits.
Lastly, there are many excellent options in the cheek area.  I would recommend you explore the possibilities with your provider.

Melvin Elson, MD · Answer

There is not reason that you cannot have Radiesse after having had Restylane or even in combination. i dont know what new procedure is being discussed as these are not new at all. while it is true that Radiesse is not reversible by injection over a period of time it does disappear completely leaving your natural collagen as the correction filler

Is ok to mix Radiesse with Restylane in the cheek area?

Answers (8)

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