It is safe to have Botox in face 1 week before total knee replacement?

There is no reason that Botox can't be injected one week before knee surgery, whether cartilage shaving or knee replacement. Nor is there an effect of the surgery on Botox injections.The information provided in Dr. Shelton's answer is for educational purposes only and is not intended to constitute medical advice.  The information provided should not be relied upon as a substitute for consultations with a qualified health professional who may be familiar with your individual medical needs. 

Hello, thank you for your question! Botox should not impact your knee replacement surgery recovery or visa versa. You will address your medical history with your certified and reputable injector, so just be sure to share your surgery and see what they say as well.

Thank you for your question.Botox should have no negative interaction with your total knee replacement. I would recommend you let your surgeon know prior to the surgery in case he has any special instructions for you preoperatively.