Which one is better: Vitrase vs Hylenex? Why doctors choose to carry one over the other?

Question

Has anyone experienced one to be better than the other in dissolving Juvederm Ultra Plus XC?(Hylenex vs Vitrase) I received 3 vials of Juvederm Ultra Plus XC in my cheek area and want to get rid of it ALL! Not only is the filler too much, but it's also placed incorrectly. Instead of looking rested and refreshed,my face looks asymmetrical dull and more tired. PLEASE HELP as I have a family wedding coming up and if someone can please recommend any doctors in the greater NYC area to help dissolve!

Sheryl D. Clark, MD, FAAD · Answer

Dear Shy1215:I have used both. They are identical in their effect. They both work very quickly to dissolve all of the hyaluronic acid fillers, including Juvederm.  Some benefit is often seen within hours.Some think that since Hylenex is a human recombinant product, there may be a lower incidence of allergic reactions with this product. Having said that, I have never seen an allergic reaction with Vitrase.All the best to you!Dr, Clark

Todd B. Koch, MD · Answer

Pretty much all Hyaluronidase is the same just different manufacturers.  Personally I use Hylenex. I have not had too many issues dissolving hyaluronic acid products.  I would recommend a second opinion.

Steven F. Weiner, MD · Answer

Hylenex is human recombinant hyaluronidase. It is exactly the same as your own body produces. It is a bit more expensive than the others but there is no chance of an allergic reaction. Vitrase is ovine  (sheep) hyaluronidase. This can rarely cause an allergic reaction. There seems to be a higher incidence in people allergic to bees. Both are effective. I only use hylenex now.

Steven Wallach, MD · Answer

I have used hyaluronidase in different forms, and I honestly can not tell the difference as to which one might be better. Best of luck.

Which one is better: Vitrase vs Hylenex? Why doctors choose to carry one over the other?

Answers (4)

Answer: Hyaluronidase

Answer: Hyaluronidase

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Everything you need to know about Juvederm

Our mission is to create a world where every investment in modern beauty is Worth It.

Which one is better: Vitrase vs Hylenex? Why doctors choose to carry one over the other?

Answers (4)

Answer: Hyaluronidase

Answer: Hyaluronidase

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Recommended reading

Everything you need to know about Juvederm

Our mission is to create a world where every investment in modern beauty is Worth It.