I'm male and always had sinus issues because of allergies. I only have that sudden onset of swelling which changes from eye to eye, never both at the same time. Also changes from upper cheek to chee. Hurts when I apply pressure on filler. Feel the discomfort when I smile or wink. No redness which rules out biofilm or infection. received juvederm in my nasolabial folds and those never hurt. Occurs once a week usually then is completely resolved the next day. Plastic surgeon thinks it's allergies.