Dear SpongeBob Great question! In a word, yes. This is a very common scenario in my practice. There are a number of considerations to keep in mind. 1). What type of implants, how long have they been in place, sub muscular or not, and how well are they positioned. If the implants are older it might be advisable to replace them at the time of the reduction. 2). How much smaller is desired, correlated with how much breast tissue can be removed. It is common to remove and replace implants and simultaneously perform a breast reduction. Some women option to remove implants and lift breasts, sometimes adding fat, in order for all breast volume to be natural. But, and this is a big "but," implants will provide more fullness on the upper half of the breast. The link below demonstrates a breast revision surgery that included a small reduction on the left. Best of Luck, Dr. Jim Romanelli