Can Bellafill form nodules after 15 years?

Question

Concerned about the long term effects of having Bellafill in my face. I read that after even 10 years nodules can form even in patients with no complications. Is this true?

Raffy Karamanoukian, MD, FACS · Answer

Bellafill can cause late occuring nodules and I have seen this specifically in my Los Angeles office. Reversal or surgical removal is necessary.

Best, 
Dr. Karamanoukian
Realself100 Surgeon

Milan Shah, MD · Answer

Bellafill is a dermal filler that is commonly used to treat wrinkles, scars, and facial volume loss. It contains a combination of collagen and polymethyl methacrylate (PMMA) microspheres. The microspheres provide a longer-lasting effect by stimulating collagen production over time.While Bellafill is considered a semi-permanent filler with longer-lasting results compared to some other fillers, the potential for the formation of nodules is a concern that has been reported in some cases. Nodules are small, raised bumps or lumps that can form under the skin.The risk of nodule forming can depend on various factors, including the individual's body's response to the filler, the injection technique used, and the skill of the practitioner administering the treatment. It's important to note that while most adverse reactions to Bellafill tend to occur within the first several months after treatment, delayed reactions are possible.

Can Bellafill form nodules after 15 years?

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