Laid down after Botox, now uneven smile. Is there something that can be done or should I give it more time? It's been 12 months.

I'm sorry this has going on for so long, but after 12 months I do not believe it is caused by your Botox injections. I think you should see a specialist to figure if you've had a Bell's palsy or another neurologic condition that has caused this to occur. 
Best wishes, Dr. ALDO 

Thanks for your question. Laying down after having a Botox treatment should not have any negative consequences. Additionally, since this happened one year ago, the Botox that was injected at the time has completely worn off. With that being said, it is highly unlikely that the Botox treatment has contributed to an asymmetric smile. I highly recommend that you have a full evaluation by your primary care physician to get to the bottom of the facial asymmetry, especially if you are experiencing any type of facial paralysis. They will be able to review your medical history and run tests to help determine the cause of your concerns. Best of luck.

Unfortunately the facial asymmetry you are noticing has nothing to do with the Botox injections you had. The effects of Botox lasts only for a few months.  Six months at the most, in a few cases a bit longer. I would suggest you see your physician for a thorough evaluation.

Your symptoms are most likely due to something else, not due to the Botox. You should see your general physician for an evaluation and work up.  Botox does not last more than 3 to 4 months and it does not typically affect the cheek when injected into the crow's feet area. 

That would be very unusual, since Botox always wears off within three months.
Generally, if Botox causes any unwanted effect, increasing the movement of the involved muscles will help the Botox wear off faster.  
Your treatment site would then revert to your baseline without permanent sequela.