Questions relating to starting and stopping a medicine should be directed to the doctor who is prescribing the medicine for you. From a general medical standpoint, the right time to discontinue Accutane (and call it a day), is when the Target Dose (calculated approx as, your weight in kilograms multiplied by 180) versus the total dose you’ve taken (adding up the total number of milligrams you’ve taken since Day 1). A patient who weighs 64kg who takes Accutane for acne will need a total dose of approx 64x180 11,520 mg. If you take 40mg each day, then you’ll reach target after (11,520/40) 288 days which is 9 months. If your dose is 80mg, you’ll reaching taget in half the time etc. Suppose your skin is clear after 5 months? Well, that’s why we doctors have to assess the risk vs benefit.