I want to know if losing the connective tissues in the skin makes it look spongy and loose? (Photos)

(That's what happened to me after hyaluronidase). I want to know if losing the connective tissues in the skin make it look spongy and loose (that's what happened to me after hyaluronidase which is not my main topic here) and if the skin loses its connective tissues, do they grow back? What are they and how can I help my skin to get them.