Touch ups, if needed, can be done 4 months after first injection or in a little as two weeks post injection.For facial rejuvenation I would suggest a combination approach of :1) skin care with products and PRP/microneedling2) PDT light therapy few times a month with growth factors3) laser treatments like clear and brilliant regularly and a few times a year Fraxel, Viva, Co2/Erbium4) Sculptra injections a few times a year for collagen production with fillers like juvederm/restylane/belotero/radiesse/bellafill5) thermage/ultherapy for yearly skin tightening with or without PDO or cone based instalift threads for lifting6) botox every 2-3 months to stop movement lines and prevent lines at restBest, Dr. Emer