Thank you for the question and congratulations on your decision to proceed with breast reduction surgery; this operation tends to be one of the most patient pleasing operations we perform. There is no direct correlation between the amount of tissue removed and the ultimate cup size that a patient will wear after breast reduction surgery. There is simply too much variability among bra cup manufactures to make it a useful metric when it comes to preoperative communication and/or post operative predictions. For example, I do not think that the generalizations of "200 cc equates to 1 cup" hold any validity or are helpful in any specific or practical way. In my practice, I ask patients not to communicate their goals, or evaluate the outcome of the procedure performed, based on cup size references. Before undergoing the breast reduction procedure it will be very important to communicate your size goals with your surgeon (who you should choose very carefully). Most patients wish to achieve enough of a reduction to help with their symptoms while remaining proportionate with the remainder of their torso. With the goal of improving communication with my patients I find the use of photographs of “goal” pictures (and breasts that are too big or too small) very helpful. For example, I have found that the use of words such as “natural” or “C cup” means different things to different people and therefore prove unhelpful. Also, as you know, cup size varies depending on who makes the bra; therefore, discussing desired cup size may also be inaccurate. Once you have communicated your goals carefully, your plastic surgeon will be able to provide you with an estimation of how much tissue will need to be removed, in order to achieve your desired outcome.Sometimes, breast reduction AND augmentation (use of breast implants focuses can be done safely at the same time. In these cases, it may be the appropriate operation given a patient's anatomic starting point and desired outcome. During this operation, some breast tissue is removed and breast implants are utilized for volume/fullness. In other cases, patients are better off under going to breast reduction procedure first; longer-term determination of whether breast augmentation would be beneficial may be appropriate. In other words, best individualize every patient's treatment plan based on her unique circumstances, anatomy, and goals. During this decision-making, safety consideration and avoidance of complications, should be paramount. My best advice: select your plastic surgeon carefully. Make sure that he/she has significant experience achieving the types of outcomes you will be pleased with. Then, communicate your goals carefully, as discussed above. Working together you will come up with a good plan to achieve your goals. Best wishes.