What can a 72 year old woman do to improve sagging breasts due to yo yo weight loss over many years?

Following significant weight loss, there is always looseness of the stretched out breast skin as the skin is no longer filled out.  Add to that the natural loss of elasticity in breast skin and soft tissue with aging, and the result is deflated, saggy breasts.  As a woman ages, the actual breast glandular tissue is replaced by fatty tissue to a significant degree.  Therefore, with weight loss, the breasts will decrease in size even more.  To treat this situation, a breast lift (a skin tailoring or tucking procedure) is the  number one treatment, as it reshapes the skin that supports the breast.  In addition, if your breasts are pretty flat with minimal volume, then you will need to consider adding volume via a breast implant or your own fat grafting, as the extra volume will help fill out the skin and create more youthful firmness.  Seek out a board-certified plastic surgeon who is experienced in breast surgery, especially in older patients and those who have lost significant weight.

Arrange a consultation with a fully qualified plastic surgeon to discuss your options and determine your suitability for surgery.  Its possible that a breast lift will help address your sagging breasts.

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Without a picture, it would be difficult to be sure, but I think you would probably require a breast lift (mastopexy).  The larger issue is whether you should undergo that procedure. In other words, are you a young, healthy 72 or do you have medical problems such as heart disease, poorly controlled high blood pressure, etc.  Your plastic surgeon will be able to guide you through the process of deciding.  Good luck.