Spironolactone and DIM?

Question

Hi there! I have mild but persistent acne on my jawline and cheeks. I was on Diane-35 for 3 years which completely cleared up my acne - but I stopped 1 year ago. 6 months ago I began breaking out again. My aesthetician told me to take Osmosis Skin Defense supplements (3 per day) which I'm not sure has helped. I just received a script for Spiro - should I take both together? Will this increase effectiveness or should I stop taking DIM and take Spiro alone? Thanks so much

Anna Chacon, MD, FAAD · Answer

Spironolactone (Spiro) is commonly used to treat hormonal acne, especially in women who experience it around the jawline and cheeks. It works by blocking androgen receptors, and therefore reducing the impact of hormones that can trigger oil production and acne. 
Regarding your question about combining spironolactone with Osmosis Skin Defense supplements, it's important to discuss this with your healthcare provider or a dermatologist. They can provide guidance based on your individual health history and the specifics of your acne condition.
DIM (Diindolylmethane), one of the main components of Osmosis Skin Defense supplements, is a natural substance produced when the body breaks down cruciferous vegetables. Some people claim it helps with hormonal balance and consequently with hormonal acne, but more research is needed to fully understand its effects. 
While it's not typically harmful to take DIM and spironolactone together, it's crucial to ensure that the combination won't interfere with your overall health or other medications you might be taking. Always consult with your healthcare provider before starting or altering any medication regimen.

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