What is the difference in technique used for fillers in men vs women when cheekbone augmentation is desired? Since male and female aesthetic standards for cheekbone differ. In my opinion: Filler should be injected into the high lateral cheekbone and on the bony prominence (apple) of the cheekbone, while anterior cheekbone injection should be a bit more conservative to create a more chiselled look instead of the typical round female cheekbone look.