Regarding PRP for hair loss; what is the difference between injecting PRP versus using PRP with microneedling on the scalp?

As with many of the procedures utilizing PRP, there is no absolute standard of care. Many will apply PRP topically allowing for absorption via portals created by microneedling while others will inject and still others will employ a combination of both techniques. Ultimately, the goal is to deliver growth factors to the site of injury/inflammation promoting rejuvenation.
Without good randomized data, it remains unclear which approach is best. It is likely that the difference between the approaches is negligible as long as the PRP is delivered where it is needed most (either topically or via direct injection or both).
As always, discuss your concerns with a board certified plastic surgeon (ABPS).Donovan Rosas MD
Board Certified by the American Board of Plastic Surgery
Member: American Society for Aesthetic Plastic
Surgery, American Society of Plastic Surgeons
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Hello and thank you for your question. Personally I use and prefer injections because it goes deeper into the skin. Depending on where you get PRP, not everyone can administer the injections. I’m not sure if there is research showing these results, but it is my preference. Best wishes.Dr. T