Would taking Manuka honey which is shown to have trace amounts of botulism affect botox and create resistance?

There are no known studies that suggest any negative interactions between honey and Botox. Consumption of Manuka honey should not effect your results. I would suggest consulting with the rendering physician regarding concerns such as this. Best, Dr. Emer. 

Hi liliruss, Both purified bee toxin and Manuka honey are touted to act like Botox, with reparative qualities to boot. There are no studies that can prove that taking it causes resistance to Botox. All the best,Justin Harper, M.D.