Thank you for asking your question. I have not heard of any detrimental issues with herbal supplements and botox (wrinkle blocker) effect. However, many supplements are potent blood thinners to include the garlic you listed. They are too numerous to mention here, but others include: gingko, ginseng, glucosamine, omega oils, flax, chia, Limu, and many more. This can lead to unwanted, excessive bruising that can cause the wrinkle blocker injections to over spread to areas you don't want, which can lead to drooping or others unwanted effects. I advise my patients to avoid anything that thins their blood that isn't prescribed by their physician for a week or so before injections whenever possible to minimize these risks. Once the injections are performed then you can resume all your usual supplements. There is a warning if you are taking a prescribed aminoglycoside antibiotic or other agents interfering with neuromuscular transmission (e.g., curare-like agents), or muscle relaxants, which should be observed closely because the effect of botulinum toxin (Botox, Xeomin, Dysport etc.) may be potentiated (increased). On the alternative side, Zytaze is an oral "supplement" of zinc and phytase, and has in some studies shown an enhancing effect upon Botulinum injections in terms of potency and longevity of result for both functional (medical) and cosmetic uses. Zinc is important for the botulinum uptake and effect, and the phytase helps with the GI absorption. The zymase is started orally before you go in for your injections. Best regards.