Hello, Thank you for your question! I do 2-3 profound treatments a week and many of them are combined with fillers. The only caveat being I donthe filler immediately after the profound treatment and not before. It would be great if it could be done before the profound bevsuse there is zero swelling but the heat from profound could alter the filler. In some rare cases patients swell early than others (like during the actual treatment) and I will recommend waiting 4-6 weeks afterward in these patients. Profound is usually come to the lower face and neck so the above doesn’t really apply to cheek or lip filler. I hope that helps!Dr G