How Long Does Xeomin Last?

Does Xeomin last longer than Botox? How long is Xeomin expected to last, approximately?

Doctor Answers 18


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Different people respond differently to the various brands of botulinum toxin (Botox, Xeomin, Dysport, Myobloc).  In general, they all last about the same.  My recommendation is to try them out and see how you respond.  There is no toxin that last twice as long as the others.  If one lasts longer in you than another, it is a matter of days, not weeks or months longer.  So it really is not a consideration when choosing your injectable.


Good luck.

How Long Does Xeomin Last?

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Based on my experience, and as confirmed by the literature I've read, Xeomin is essentially interchangeable with the other neuromodulators in terms of effectiveness and duration of correction.  Dosaging is different (100 units of Botox = 100 of Xeomin = about 300 of Dysport) but assuming equivalence of dosage (and how fresh it is, etc) they are largely similar treatments.

I hope that this helps and good luck,

Dr. E

Longevity of Xeomin

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For most people the results of Xeomin is about the same as other wrinkle reducers, and depends on the dosage and probably the genetics of the person, and exact placement of the product.

Of my 9 staff, only one found that Xeomin didn't last as well for her, when we all tried it when it first came on the market.

When it first came out, some of my patients thought it worked at their crows feet better than other toxins they had tried.  It hasn't been around for years yet, so as we all gain more experince with it, more answers and impressions may be available.

Smaller doses will last less long than a stronger dose, all else being equal.

Deborah Ekstrom, MD
Worcester Plastic Surgeon
4.7 out of 5 stars 39 reviews

Clinically, these two products behave the same.

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While there is really not good science to supprot this conclusion, some believe that the effect kicks in a little faster than BOTOX.  I am not sure I believe this.  However, on longevity, there is no clinical difference:  treatment lasts about 4 to 6 months.  

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

How long does Xeomin last?

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Both Xeomin and Botox have as the active ingredient botulinum toxin A . So for all practical purposes their pharmaceutical effects are the same. Xeomin lasts about as long as Botox, 4 to 6 months realistically,  3 to 4 months.

Xeomin duration

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Xeomin tends to last about the same amount of time as Dysport or Botox, in that all three products will last around 3-4 months in most patients.

All the best,

Matthew Richardson, MD
Frisco Facial Plastic Surgeon
5.0 out of 5 stars 7 reviews

About the Same as Botox

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Xeomin and Botox are identical products in terms of use and efficacy.  According to dozens of scientific medical studies to determine the difference of human response to Botox vs. Xeomin have shown them to be equal. Xeomin is the name of the Merz company product of "ultra pure" Botulism toxin. It is identical to Botox in virtually every way, even so far as it's effects on facial muscles and for migraines. Any differences noted in the time of uptake, longevity of action, diffusion to other ares, or any other patient described effect, are purely differences of drug dilution and technique of administration by the practitioner. Of course, rubbing the area, lying down or exercising after treatment, having a cold or flu in the timeframe related to administration, other incidental medical issues, etc. may all have an effect on the response to the product. Hope this helped!

Dr. S

Bruce Saal, MD
Los Gatos Dermatologic Surgeon
5.0 out of 5 stars 2 reviews


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Xeomin typically lasts the same amount of time as botox. I have seen people metabolize botox and xeomin differently, however the duration is usually 3-4 months.

How long does Xeomin last

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Xeomin has the same active ingredient as Botox and we expect it to last about the same amount of time as Botox.  Xeomin has no preservatives so some practices are finding because of this it lasts a week or two shorter though in my practice I find it is interchangeable with Botox and patient satisfaction is just as good if done properly. 

Mike Majmundar, MD
Atlanta Facial Plastic Surgeon
4.5 out of 5 stars 50 reviews

Xeomin lasts about 3-6 months

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Thanks for your question. The effectiveness and duration period of Xeomin and Botox is quite similar: they generally need to be injected every 3 to 6 months. Xeomin requires about 1 week to see its full effect, whereas the onset of Botox is 3 to 4 days.

Cory Torgerson, MD, PhD, FRCSC
Toronto Facial Plastic Surgeon
4.7 out of 5 stars 170 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.