I Have Always Used but Botox but Tried Xeomin Recently and Haven't Had Great Results. Am I Resistant?

You may need more units applied to the area to see full correction, seek a reputable physician who can provide you with the result you wish to achieve 

I would echo what has been said by previous doctors. My preference is for injecting Dysport due to my experience with Dysport having increased potency and onset of action. However, when looking at longevity between Xeomin, Dysport, and Botox, all three neurotoxins last about the same time based on clinical return of brow movement. If you're a purist, then Xeomin has no associated protein attached to it, so it may be best for you. I've also never seen a Botox allergy. 

Hi Lili.  Botox and Xeomin are very similar products.  Both are Botulinum Toxin type A.  It would seem unusual to us that you would receive no benefit from Xeomin for the same dose of the two drugs.  What we have found is that 20 units of Xeomin may not last as long as Botox, but Botox, Dysport and Xeomin all do a very good job of relaxing muscles they are injected into.  Botox line is that there are patients and practitioners that prefer one or the other and if you are a person that really likes the results of Botox, then by all means, switch back.  Best of luck.

Hello and thank you for your question!  It sounds like you have a good relationship with your injector.  I would recommend speaking with them regarding your concerns.  With the different neurotoxins, you may also require a different dosage.  Once you reach your desired outcome, you should be pleased with your results.  However, if you prefer to return to Botox since you know that it was effective, there will not be a problem doing so.  Best of luck to you and I hope this information is helpful!

While the manufacturers of each product will tell you that it is not the case, in my experience, some patients occasionally do seem to respond better to one product over another. While there could be other factors involved, such as how long ago the particular product was reconstituted, the number of units that were used, or the specific injection technique, it still seems that some patients may respond better to one particular product. I tend to keep patients with a particular product unless they experience a problem or have a good reason to switch, but there is no harm in going back to a product that worked better in the past.All the best,

The active drug in each of these products is the same, therefore treatment outcomes should be similar.  There is no question that some patients prefer one product over the other.  They are not interchangeable from a dosing standpoint so it may be that the dose of Xeomin you received may need to be adjusted. 

My patients have done very well with Xeomin injections, particularly those who have used Botox for years and have developed a resistance to Botox. Surgery90210

  It is quite unlikely that you developed resistance to Xeomin.  Although it is quite rare, patients are much more likely to develop resistance to Botox.  It is possible that your Xeomin dose needs to be tweaked, for best results.

There shouldn't be a reason that any one of the three botulinum toxins, Dysport, Botox or Xeomin, is signficantly better than the others.  One patient may like one, whereas another patient may prefer the effects of another. Some may say there product works a day or more sooner and others may say there is less free protein to cause immune reactions but I the three products may be quite similar.  The number of units for each to be equivalent, may differ and more studies may need to be done.

I agree with others who have posted on this topic.  I have found that Botox, Dysport, and Xeomin are all efficacious.  Some patients do better with Botox than Xeomin or Dysport and vice versa.  Allergan has the lion's share of the market, but this is likely to change over time.