Is it possible to only dissolve some filler?

Hello! My name is Jessica, I am a physician assistant, and one of the providers at Aesthetic Skin - Winnetka & Chicago. This is a great question. Yes, it is absolutely possible to dissolve only some of the filler rather than all of it. If you're experiencing puffiness or mild migration in the cheeks from filler placed three years ago, hyaluronidase—a medication that dissolves hyaluronic acid-based fillers— can be used to target specific areas. The goal would be to reduce volume where it's no longer flattering or has shifted, while preserving the structure and support in areas where the filler is still beneficial. This approach allows for a more balanced and refined result without having to start over completely. I hope this helps and best of luck!

Unfortunately, you have provided little history and no photos. So, it is very difficult to accurately answer your question. It would be important to see what kind of migration you are referring to, which may not be migration at all and simply age related loss of volume. Secondly, it is important to know what kind of filler was used: permanent, semipermanent, or temporary. For example, the duration of the benefits of even robust HA fillers used for cheek augmentation may last only 1.-1.5 years. So, the descent you are experiencing may not be from migration, but from natural loss of the filler over time.
And finally, as to your question of whether a dissolvable HA filler can be partially dissolved, the answer is often it can often be when carefully performed in expert hands, using appropriate dilutions of the dissolving enzyme. You would be wise to seek consultation with an experienced, board certified cosmetic dermatologist injection expert. Hope this helps and best of luck.