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Is Restylane safe? Restylane has BDDE in it. On the FDA website it says it can increase risk of cancer

Restylane has BDDE in it. On the FDA website it says it can increase risk of cancer. they found this after a clinical trial on mice. Is this true?

Answers (2)

From board-certified doctors and trusted medical professionals
Dr. Jason Emer, MD
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Dr. Jason Emer, MD
Dermatologic Surgeon, Board Certified in Dermatology
4.7 | 533 Reviews
Answered on Apr 30, 2015
Answer
Dr. Steven Hacker, MD
Dr. Steven Hacker, MD
Dermatologic Surgeon, Board Certified in Dermatology
Answered on May 2, 2015
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More Restylane Questions

5 days after fillers, my tear trough is again becoming hollow. I had 2ml Restylane, 1ml for each eye (Photo)

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Jeff Angobaldo, MD

Thank ypu for ypur question.  You have a improved result after filler. Your still swollen after your filler injection and the swelling will last for another 1-2 weeks.  I would not advise adding more filler to the area.  Discuss your concerns with ypur injector.

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I had restylane for a non surgical nose job to disguise the bump on the bridge of my nose. Is this swelling? (Photo)

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Jeff Angobaldo, MD

Thank you for your question. Your still swollen after your filler injection and the swelling could last for another 1-2 weeks. You never mentioned how much filler was injected but the area will swell.  The nasal dorsal injections are very satisfying for patients. Don't worry, if you have...

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How much swelling is normal after Restylane injections under the eyes/upper cheeks? (photos)

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Nima Shemirani, MD

Hi @rachela56! Swelling and bruising are common after dermal fillers. It should take 1-2 weeks to subside. Best of luck, Dr. Nima!

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Best treatment for deep under eye hollows. Tear trough injections, fat grafting or Restylane?

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Marwan R. Khalifeh, MD

Our office prefers to use Restylane in the under eye hollows. The reason for this is Restylane has finer particles than fat itself, and thus lends itself to settling and adhering to the under eye area more naturally and noticeably. For this reason the best results are seen with Restylane....

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I had restylane injected into my tear troughs. It is 6 days since my injections. Is this normal swelling or overfill?

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Daniel Levy, MD

Rya,Thanks for sharing your photos and story.  Uneven tear trough contour after Restylane can happen.  This can be due to how the injection was performed, which plane of tissue it was placed, how much post-treatment massage you had, or the overall amount amount of filler injected....

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Had bad results with Restylane filler. Is PRP (platelet rich plasma) a better option for me?

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Jason Emer, MD

I think its the person injecting that gives you the results you are looking for.  Many of my patients do fillers in this are and PRP a few times a year to maintain the results.  PRP is not a filler but rather a stimulator. Cannula injections limit complications and give a more...

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