I wanted to know should hyaluronidase always work for Restylane?

Hyaluronidase should work nicely to dissolve some or all of the restylane (hyaluronic acid) filler. Sometimes more than 1 treatment is needed, and the volume and the concentration of hyaluronidase that's injected is important too, so you really want only an expert physician such as a dermatologist doing this for you. While we typically keep ours in the fridge, it can be kept out of the fridge. It shouldn't be expired, but it needn't be "fresh" either.

Thank you for sharing your question. Yes, Hyaluronidase
should dissolve Restylane, however it may require a series of treatments with
hyaluronidase in order to ensure that all filler has been dissolved. To answer
your second question, hyaluronidase must be refrigerated for storage and
efficacy. For more information, I recommend following up with your injector to discuss
any other questions you may have regarding hyaluronidase. Best, Dr. Griffiths.