Is there a connection with having Lipoma and joint pains? For being 29, I do not feel that I should have so much joint pain all over. My joints always hurt and my knees get stabbing pains at random times,I want to cry sometimes from it. I have a large one that causes pain in my back. I do not think it could affect my hands. I have been told it is not arthritis and no Dr has ever known enough about Lipoma to answer any questions. They just say the same thing, "not much is known why, what or how"