Lip filler: does hyaluronidase also break down your natural HA in face?

Thank you for your question. Yes, the hyaluronidase is very effective in dissolving hyaluronic acid, however, it is unable to distinguish between the filler and your own, and therefore in my professional opinion it has to be used very selectively and only one strictly necessary.

All the best

Andrea Marando
Plastic and Cosmetic Surgeon
Manchester and London, UK

Hyaluronidase enzyme continues to be an excellent option for patients with fillers that need to be dissolved. Fillers can swell and migrate unpredictably, especially when a filler with a high-edema quotient is used in thin areas. Our office uses disciplined approaches to help patients with acute or chronic issues related to hyaluronic acid fillers. We begin by assessing for any tissue compromise and advocate early treatment to avoid complications with vascular occlusion. In chronic issues, it is important to gradually break up and dissolve filler so there is no further migration of loose filler substrate. Conservative staged dilution may also help avoid volume loss. If the filler is not dissolving, we may consider stronger concentrations or surgery.

Best,
Dr. Karamanoukian
Realself100 Surgeon