What is the Likelihood of an Allergic Reaction to Juvederm after a Reaction to Botox?

Allergies to Botox and Juvederm, and Restylane, are extremely rare. If you had a reaction, it might be a different type of reaction other than allergy. The botox molecule and the hyaluronic acid molecule in Juvederm are completely different, so even if you were allergic to one, you shouldn't be allergic to the other.

Assuming that you in fact had an actual allergy to BOTOX, the likelihood of you also having an allergy to Juevederm is very low but not zero.  If you are concerned about this, I recommend that you have your cosmetic surgeon apply a test injection of Juvederm somewhere inconspicuous like the arm.  If you have no reaction to the injection after 10 days then it is improbable you will have an issue with the product.  Just remember that allergies can develop anytime.  So if you think you are having a problem, immediately bring this to the attention of your injecting physician.

Having had a reaction to Botox does not put you at increased risk with Juvederm.  The two are completely unrelated and do not have cross-reactivity.

 

Mark Lucarelli, MD, FACS

Madison, WI

Botox is onabotulinum toxin type A (a form of neurotoxin) and Juvederm is made from hyaluronic acid ( a form of tissue glue found throughout the body).  These are chemically dissimilar, achieve different effects, and are used for different purposes.  There should be no cross antigenicity between these products, which are both made by Allergan.

Botox and Juvederm are completely different products with different chemical structures.  Being allergic to one product will not make you allergic to the other.  If you have concerns, you can have a small test site injected with either product.