Missed Period on Spironolactone

Question

I've been on Spironolactone for about 9 months now, I started on 100mg and have moved down to 75mg in the last month or so. I haven't got my period since I started, which I know is normal but I was under the impression it "could" come back on a lower dosage. How long does it take to see the effects if my period will come back? And at what point should I try a lower dosage again?

Anna Chacon, MD, FAAD · Answer

Spironolactone is often used in dermatology for its anti-androgen effects, particularly in the treatment of acne and other hormonal skin conditions. It’s not uncommon for menstruation to be affected while taking this medication, as it can influence hormone levels.

The absence of your period (amenorrhea) while on Spironolactone can be due to its impact on your body's hormonal balance. While some individuals do experience a return of their menstrual cycle after reducing the dosage, this can vary greatly from person to person.

Here are some general considerations:

Time Frame: It might take a few months for your body to adjust to the lower dosage and for your menstrual cycle to return. Monitoring your cycle over the next few months can help you determine any changes.

Dosage Adjustment: If your period does not return and this is a concern for you, discussing further dosage adjustments with your healthcare provider would be beneficial. They can guide you on whether a lower dosage is appropriate or if alternative treatments should be considered.

Other Factors: Consider other factors that might be influencing your menstrual cycle, such as stress, changes in weight, exercise habits, or other medications.

Consult Your Physician: It’s important to have a conversation with your healthcare provider about your symptoms and any concerns you have. They can provide personalized advice based on your medical history and current treatment plan.

If you have any further questions or concerns, please feel free to reach out to your healthcare provider.

Missed Period on Spironolactone

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