The palm of my left hand has a 3rd degree keloid scar that is tightening. Any suggestions? (photo)

I would apply Plato's Scar Serum and consider either surgical release or Xiaflex collagenase. Best, Dr. KaramanoukianLos Angeles

This can be improved with lasers, I suggest you see a laser trained board certified physician who has a lot of experience with scars .  Best, Dr. Emer.

Custom splints can be made by a physical or hand therapist.Scar gels or sheets can be tried.The tight scar contracture can be surgically released with a Z-plasty, a Diamondplasty, or small skin grafts.Xiaflex to dissolve the scar would help, but you have some overall skin shortage from the burn and not just a scar contracture.  You may need additional skin.  I would recommend starting small with a Z plasty or Diamondplasty.  I don't feel laser will loosen up the contracture at this stage.Best wishes, Dr. Denkler

Scar tissue in this area will persist and another surgical procedure will leave scar tissue which may be worse. Silicone gel can soften the scar and advice re splints are best obtained form an occupational therapist who works with hand surgeons.