What would be the dosage for a second round of Accutane?

Question

I relapsed after 6 months of Isotretinoin. (During those 6 months, my skin was amazing, btw.) I'd been taking 20mgs of accutane every day for 6 months. The breakouts didn't appear as soon as I got off, but gradually. I must say, the breakouts I've been having are drastically lesser, but breakouts all the same. I really want to go for the second round, but the only thing I'm unsure about, is the dosage. Do i have to have it longer this time? And how much?

Amy Y. Paul, DO, FAAD · Answer

Thanks for your question.  There are a quite a few patients that need a second, or even a third course of Accutane if they have very stubborn acne, so that would be a perfectly fine option for you if you think you need it.  I might recommend increasing the dose if you did well and tolerated 20mg daily.  I usually start people at 40mg daily and we go up to three capsules daily if needed during the 6 months.  The literature does seem to indicate that a higher overall dose is usually more effective than under-dosing over time.  As long as you follow the ipledge requirements and work closely with your dermatologist, you should be able to find a resolution and proper dose for you.  Some of my second course patients end up needing a shorter course, so that is something you might be able to look forward to, but everyone is different.

Reuel Aspacio, MD, FAAD - Account Suspended · Answer

Thank you for your question. Accutane (isotretinoin) dosing is based on an individual's weight, which is 1 mg per kilogram for 4 months. Therefore, if you weigh 60 kg, then your minimum recommend total dose will be isotretinoin 60 mg per day for four months.  Some providers prefer to start patients on lower doses to help patients acclimate to any side effects and to monitor for any changes in lab work. The dose may be increased depending on your tolerance of the medication and if your blood work is normal. I highly recommend you consult with a board certified dermatologist. Take care and good luck.

What would be the dosage for a second round of Accutane?

Answers (2)

Recommended reading

Everything you need to know about Accutane

Our mission is to create a world where every investment in modern beauty is Worth It.

What would be the dosage for a second round of Accutane?

Answers (2)

Browse related questions

Recommended reading

Everything you need to know about Accutane

Our mission is to create a world where every investment in modern beauty is Worth It.