The unwanted, bluish-colored Tyndall Effect can result from too superficial a placement of a hyaluronic acid filler within the skin or injection within very fine, delicate skin, such as under the eyes. Since the duration of the effect of hyaluronic acid filler injections, with some exceptions like Voluma XC, seldom exceeds a year to a year and a half, one can reasonably expect the Tyndall effect not to persist longer than this. That having been said, I have personally treated a patient with the Tyndall effect who gave a history of having been treated in the smile lines over two years earlier with Perlane. A few microdroplets of hyaluronidase to dissolve the residual filler remedied that patient's problem within three days.