Thanks for your question. The short answer is no. However, if you are doing IPL or any other laser and wish to do Botox/Restylane/Radiesse/Juvederm, then I would suggest that you split up your treatments and do the IPL/laser separate. The only reason behind this is that IPL/laser generates heat, and this heat may affect concomitantly injected Botox or filler. In most cases this shouldn't be an issue, but you want to make sure that you get the best results from your treatment and don't want to take chances. The reverse is also important - the swelling due to IPL/laser may impact the injections of Botox or fillers, so it's best to do the IPL/laser in one appt, and Botox/fillers in another appointment. Hope this helps!