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Hydroquinone is a skin bleaching ingredient used to lighten areas of darkened skin. In 1982, the FDA published a rule to propose that OTC skin bleaching drug products containing 1.5 to 2 percent hydroquinone be generally recognized as safe and effective (GRASE). In 2006 research revealed that hydroquinone taken orally by mice or rats could cause cancer. It also has been linked with a medical condition in humans known as ochronosis (skin darkening and disfiguration) when applied topically.At that time the FDA requested more scientific testing on hydroquinone. Those tests began in 2009. On 11/17/10 the FDA recalled specific batches of Triluma, "Firm was notified by supplier of a subpotent active ingredient". That is not the same as a complete ban and the product can still be used. It contains 4% hydroquinone and therefore requires a prescription.
We recommend Melarase creams to our patients who have hyperpigmentation. There is a push" towards non-hydroquinone creams and we advocate both hydroquinone and non-hydroquinne regimens for optimal reduction of hyperpigmentation in our practice. We recommend the Revitalization Mini Kit to our...
Jamaica Skin DiscolorationDark discoloration on the legs can be treated with Melapads and Melarase creams used twice daily to the skin. Raffy Karamanoukian MD FACS
Melarase creams and Melapads are excellent skin lightening creams for the hands, toes, and feet. Dark discoloration of the extremities takes a few months to lighten. Best, Dr. Karamanoukian Los Angeles
There are several prescription and non-prescription skin lightening products available to address your problem, for example, hydroquinone, any of which may or may not be appropriate, depending on your skin type. The key in the use of these products is not to use them to the point of causing...
Dark armpits are common and hyperpigmentation may occur in areas of the skin that experience constant rubbing of skin such as the thighs and armpits. I advise patients to begin Melapads, Melarase PM, and the Body Brightening kit if the pigmentation is severe. Best, Dr. Karamanoukian Los Angeles
In my practice, I try to stay away from these combination regimens, as cortisones are non-selective inhibitors of melanocytes. I would recommend my patients to start Melarase AM and Melarase PM for the pigmentation. I would start with an intense skin rejuvenation protocol for age spots that i...
