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Can I use hyaluronidase on lip scar tissue? (photos)

jzuliAug 3, 2019
Hello, I had a bilateral cleft and had lip filler for the past 10 years. I find them too big since my last injection (Restylane Kysse, 15 months ago) and the HA doesn't seem to resorb much. Can I do hyaluronidase? Also, I noticed a sort of big blister that formed on the top of my upper lip. Is it due to lip filler? Thank you

Answers (3)

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Dr. Jason Emer, MD
Dermatologic Surgeon, Board Certified in Dermatology
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Answered on Aug 7, 2019
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Dr. Aaron Capuano, MD, FACS
Board Certified Plastic Surgeon
Answered on Aug 8, 2019
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Dr. Shaun Patel, MD
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Answered on Aug 6, 2019
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Raffy Karamanoukian, MD, FACS

Longterm filler problems include migration, edema, and nodularity. Filler migration and permanence is a very common problem because there are many different types of HA fillers on the market and each is specified for a specific part of the face. Use of highly cohesive fillers on thin skin may...

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Kenneth D. Steinsapir, MD

Most injectors really don't understand the filler and their physical characteristics. They also don't understand the use of the enzyme. Runny fillers like Restylane Refine and Define need much more enzyme to remove than high G prime fillers like Restylane or Lyft. Restylane Refine was an effort...

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Josie L. Tenore, MD

Great Question!  There is a LOT of variation in fillers so there isn't a set "dose" that works for each type. In the literature, the easiest fillers to dissolve are Boletero and Voluma being the most difficult to dissolve. Because of the differences in fillers, the range for dose is...

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Raffy Karamanoukian, MD, FACS

Hylauronidase has many advantages and should be considered in patients who are unhappy with their results or in acute cases of overfilling or occlusion. Its often better to reverse filler and restart then to deal with long term edema. Filler migration and permanence is a very common problem...

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Raffy Karamanoukian, MD, FACS

Hylauronidase has many advantages and should be considered in patients who are unhappy with their results or in acute cases of overfilling or occlusion. Its often better to reverse filler and restart then to deal with long term edema. Filler migration and permanence is a very common problem...

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Mayli Davis, MD

I’m sorry to hear the problems you are having.  Unfortunately, saline will only plump the skin for a few hours.  You should consider adding back filler and use topical hyaluronic acid stimulators such as Skinceuticals hyaluronic acid booster.  I agree hyaluronidase should b...

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