Is it possible to create dimples with Botox?

Unfortunately, you won’t be able to achieve dimples using BOTOX®. This injectable works by temporarily relaxing the muscle contractions in the upper portion of the face that cause expression lines and, eventually, permanent wrinkles. The presence of dimples, on the other hand, is caused by a facial muscle that is shorter than normal. Because this is a genetic condition, there is not much you can do to create them artificially.

Dimples are indentations in the cheeks due to a defect in the buccinator muscle and muscle insertion at that location. Botox can only relax muscle. Botox can not create a dimple.Andrew Campbell, M.D.Facial Rejuvenation SpecialistQuintessa Aesthetic Centers

Dimples are awesome, but can not be done with Botox.  Dimples can be done surgically and his come out the most natural I've seen.  Botox is better for gummy smiles or wrinkles around the eyes and for muscle hypertrophy, like the masseter.  Hope this helps.