It's understandable that you're seeking effective treatment options for your long-standing dark circles. Both polynucleotides and fillers are potential treatments, but they address different aspects of the problem and come with their own benefits and risks. Let's break down each option: Polynucleotides Polynucleotides are relatively new in the aesthetic field. They are derived from DNA and are believed to help with tissue regeneration and repair, improving skin texture and health. Here are some potential benefits and considerations: - **Benefits**: - Can improve skin quality and elasticity. - May help with pigmentation issues to some extent by promoting healthier skin. - Non-invasive with minimal downtime. - **Considerations**: - Limited long-term data on efficacy and safety. - May require multiple sessions for noticeable results. - Results can vary significantly between individuals. Under-Eye Fillers Fillers, typically hyaluronic acid-based, are more commonly used for addressing hollowness and volume loss under the eyes. Here are the benefits and considerations: - **Benefits**: - Immediate improvement in under-eye hollowness, which can reduce the appearance of dark circles. - Long track record of use with established safety profiles when performed by experienced practitioners. - Results can last from several months to over a year, depending on the filler used. - **Considerations**: - Risk of complications such as swelling, bruising, or, rarely, more severe issues like vascular occlusion. - May not directly address pigmentation; best for hollowness. - Requires skilled and experienced practitioners to minimize risks and achieve natural-looking results. Recommendations Given your description of both hollowness and discoloration, a combination approach might be most beneficial: 1. **Consultation with a Dermatologist or Aesthetic Specialist**: This is crucial to tailor the treatment to your specific needs. They can assess the underlying causes of your dark circles and recommend the best course of action. 2. **Combination Treatments**: - **Fillers** can address the hollowness, potentially reducing the shadowing effect that exacerbates dark circles. - **Polynucleotides** or other skin rejuvenation treatments like microneedling with PRP, laser therapy, or chemical peels could help with the discoloration. Both polynucleotides and fillers have their merits, but their effectiveness can vary based on individual circumstances. A thorough consultation with a qualified professional is essential to determine the best approach for your dark circles. They might suggest a combination of treatments to address both the hollowness and discoloration effectively.