Lip Filler - Dent in lip, even after dissolving. How can I fix this? (Photos)

It sounds like the dent in your lips could be due to skin stretching from repeated filler use, uneven collagen remodeling after multiple dissolving sessions, or residual fibrosis (scar tissue) from filler breakdown. Since you’ve had filler for about a decade and have dissolved multiple times, it’s possible that your lip tissue has been affected structurally.

To improve the appearance:

Time & Hydration – Your lips may need time to naturally regain elasticity and collagen production. Keeping them hydrated with a good lip balm and topical treatments like hyaluronic acid can help.

Microneedling or RF Microneedling – These treatments can stimulate collagen and elastin, potentially helping the skin bounce back and improving texture.

PRP (Platelet-Rich Plasma) or Exosomes – Injecting PRP or exosomes into the lips could help regenerate tissue, improve elasticity, and encourage natural healing.

Laser Treatments – Fractional lasers (like CO2 or Erbium) can resurface the skin and stimulate collagen production, which may help even out the texture.

A Different Filler Approach – If you’re considering getting filler again, a strategic placement using softer, more natural products (like low-G Prime HA fillers or even a microdroplet technique-SkinVive comes to mind) may help smooth things out instead of adding bulk.

Massage or Manual Therapy – If any residual scar tissue is contributing to the dent, gentle massage (or professional lymphatic drainage) could help break it up over time.

Best of luck!
Genie Alexander, RN BSN for Anna Petropoulos, MD FRCS at Center for Classic Beauty Boston & Danvers, MA.

The dent in your lip can be surgically resected. This can be done under local anesthesia and used to invert the edges and fill out the concavity.

Best Wishes,

Gary Horndeski, M.D.

Injection of fillers into same site for multiple times (over 10 years) would create scars as a reaction to filling material, injection injury, inflammation. In a long run these scars are going to create lumps and other irregularities of the lips which may be very difficult to treat. In person consultation with an experienced ces board certified plastic surgeon would be your best starting point. Good luck.