I was on roaccutane for 6 months for 50 mg a day because of acne I suffered from really bad chapping of the lips although I am only 21 and male so I probably complain about it more than I should! But I've been off the medication now for nearly 5 months Now the line on my lower lip which separates the wet part of the oral mucosa from the front facing normal skin is dry and scaly. The oral mucosa directly behind the line is sticky to touch. I don't think you would call this chapped lips.