Before you claim this is unusual please research the very real complaints of thousands of people, globally, that have suffered due to Hyaluronidase. I was injected with hyalase to dissolve lip filler. Many practitioners claim it is not possible for it to travel to other areas of the face but this drug was literally designed to make tissue more permeable so it's not all that unrealistic. Onto skin's lack of integrity, how can I resolve indentation of skin due to disrupted HA in my skin? Not edema