I'm on Humira for psoriatic arthritis - can I do CO2 fully ablative laser?

Question

48 y.o. male. I've been on Humira for 15+ years. I am asymptomatic in terms of arthritis and psoriasis. Considering CO2 for just general skin tightening, pore reduction, etc. Thoughts??

Erik Peterson, MD · Answer

Yes, fractional CO₂ laser resurfacing can help with general skin concerns like tightening, fine lines, texture and pore improvement because it removes aged skin layers and stimulates new collagen production. It’s one of the more powerful options compared with gentler non‑ablative lasers. 
That said, CO₂ is strong and has real downtime (redness, peeling, sensitivity) and risks like pigment changes, infection or scarring if not done correctly. Healing also depends on your skin type and how your body responds. 
Because you’ve been on Humira long‑term, talk with a board‑certified dermatologist first. Immunomodulators can affect wound healing and infection risk, so having an in‑person exam ensures the laser is chosen and set up safely for you. A dermatologist can also suggest alternatives (like non‑ablative or fractional RF) if CO₂ feels too aggressive for your goals and skin. 
In short: CO₂ can tighten and improve texture, but because it’s strong and you’re on long‑term medication, a dermatologist’s assessment is key before moving forward.

I'm on Humira for psoriatic arthritis - can I do CO2 fully ablative laser?

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