Botox works by disabling the nerve signal to the injected muscles. Clinical studies show that the actual Botox substance is absorbed within 4 hours after injection. Botox lasts 3 to 4 months because that is how long it takes for the nerves to regrow their ability to send signals to the muscle, not because the Botox is physically in there for that long. With this in mind, it is unlikely your supplement will have an impact on your Botox results. Because there are minimal studies on supplements in general, there is no study I can point to that will give you a definitive answer. If you want to be on the safe side, just avoid the supplement for a few days before and after your treatment.