What is the most natural filler ?

When a patient has a history of multiple allergies or of autoimmune disease, I generally recommend using a hyaluronic acid gel filler.  Hyaluronic acid gel fillers are derived from hyaluronic acid from a bacterial source that is very similar to hyaluronic acid found naturally in human skin.  That means it is very unlikely for human skin to react to hyaluronic acid gel fillers as something foreign and they are unlikely to stimulate an allergic reaction.  Another benefit for a patient with your concerns is that hyaluronic acid gel fillers can be dissolved after implantation using hyaluronidase, an enzyme injected directly into the area of filler.It may also be a good idea to have your infectious disease/Lyme physician speak with your dermatologist or surgeon prior to being treated so that all your providers are comfortable with your care.I hope this answer was helpful.Best wishes.