Can I Have Liposuction While I'm Taking Accutane?

Accutane affects every organ in the body, especially the liver. The lidocaine tumescent solution injected during the liposuction to numb up the fat layer is filtered threw the liver as well as any IV sedation meds given during the surgery. Even tho the risk of problems is very little when either accutane is prescribed or liposuction is done alone, the combined effect could be dangerous. I would wait 2-3 months after off accutane to do the liposuction and get a blood test to make sure the liver enzymes are normal. There also is a little more risk of scarring from wounds while on accutane but this is minimal.
David Hansen, MD

Definitely no liposuction or any kind of elective surgery while on Accutane. Isotretinoin (Accutane) tends to make wound healing somewhat more challenging by creating greater inflammation, and possibly hypertrophic scarring. You may want to postpone elective surgery for 6 months after completion of Accutane.

Liposuction can be performed while on Accutane, but the scars made on the skin may not heal as well as a procedure done while off Accutane. Liposuction addresses the deep subcutaneous tissue and should not be adversely affected by Accutane.

Dear Reetha,
Good for you for asking this question as you must be careful while on Accutane. While on Accutane and for 1 year after, you should not have any surgical procedure. Once you're safely off of it and you've waited the appropriate amount of time, it is then okay to have the liposuction treatment if your doctor recommends it. Hope this helps!
Dr. S

Since Accutane slows down wound healing and can affect scarring in unpredictable ways, it seems unreasonably risky to me to have a completely elective surgical procedure while on Accutane.